Carvacrol attenuates N-nitrosodiethylamine induced liver injury in experimental Wistar rats
نویسندگان
چکیده
منابع مشابه
A diet rich in cocoa attenuates N-nitrosodiethylamine-induced liver injury in rats.
The effects of cocoa feeding against N-nitrosodiethylamine (DEN)-induced liver injury were studied in rats. Animals were divided into five groups. Groups 1 and 2 were fed with standard and cocoa-diet, respectively. Groups 3 and 4 were injected with DEN at 2 and 4 weeks, and fed with standard and cocoa-diet, respectively. Group 5 was treated with DEN, received the standard diet for 4 weeks and t...
متن کاملCarvacrol Attenuates Lung Injury in Rats with Severe Acute Pancreatitis
This study was designed to evaluate whether carvacrol (CAR) could provide protection against lung injury by acute pancreatitis development. The rats were randomized into groups to receive (I) no therapy; (II) 50 μg/kg cerulein at 1h intervals by four intraperitoneal injections (i.p.); (III) 50, 100 and 200 mg/kg CAR by one i.p.; and (IV) cerulein+CAR after 2h of cerulein injection. 12h later, s...
متن کاملGender Disparity of N-nitrosodiethylamine Induced Hepatocellular Carcinoma in Wistar Albino Rats
Cancer is particularly alarming in developing countries like India where life expectancy is increasing rapidly. Over the past 25 years the incidence and mortality rates of Hepatocellular carcinoma (HCC) are expected to double over the next 10–20 years.HCC is a transformation process of normal liver cell into a cancerous cell which involves initiation, promotion and progression stages.HCC was in...
متن کاملOperculina turpethum attenuates N-nitrosodimethylamine induced toxic liver injury and clastogenicity in rats.
The root extract of Operculina turpethum (OTE) has been used as an anti-inflammatory, purgative, and hepato-protective agent. N-Nitrosodimethylamine (NDMA) is a potent hepatotoxin that induces fibrosis of the liver. In the present study, we examined the therapeutic effects of OTE root extract against NDMA-induced hepatotoxicity and clastogenicity in rats. Hepatic fibrosis was induced in adult m...
متن کاملPunica granatum attenuates Angiotensin-II induced hypertension in Wistar rats
Acute subcutaneous administration of angiotensin-II (Ang II-150μg/kg) causes a rise in blood pressure in normal Wistar rats. Administration of Punica granatum juice extract (PJ100 mg/kg and 300 mg/kg; p.o.) for 4 weeks in angiotensin-II treated rats significantly (P<0.05) reduced the mean arterial blood pressure and vascular reactivity changes to various catecholamines. PJ treatment significant...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Food Science and Human Wellness
سال: 2015
ISSN: 2213-4530
DOI: 10.1016/j.fshw.2015.04.002